Today, if one searches a cabinet at home, there is perhaps just as much chance to find a bunch of keys as certain pills: the antibiotics. Should this medication be missing, it will be available at the neighborhood pharmacy unless the stock just ran out. Should one get to hospital and they lack it, this facility is better shut down. Antibiotics are the drugs that people turn to when they are diagnosed with common ailments such fever or wound infections. They do their ‘magic’ to restore our optimal health. Many times though, when people mention antibiotic, penicillin comes to the fore. Synonymous with antibiotic, in common mentions, penicillin is the most widely used antibiotic that has had profound impact on humanity (American Chemical Society, 2011). However, the secret of penicillin was little known until 1928 when Sir Alexander Fleming discovered it, by chance though. This discussion therefore explores the discovery of penicillin and its impact on humanity.