The use of pesticides has become widespread across the globe over the years. The effect of their use is immediate in most cases, and this makes them indispensable in most households. However, there have been cases where pesticides have been over used, sometimes with life threatening effects. In agriculture, current trends rely heavily on their use. It is important to note that the use of pesticides can also be harmful to the environment. This is because nature has its own way of creating a balance in the ecosystem. Various countries have come up with rules and regulations regarding the use of pesticides, but nonetheless, cases are still there of their overuse. This study is aimed at establishing cases of over use and the harm resulting to it on both human persons and the environment. This will be done via the use of examples of persons and cases of harm on the environment in various places across the divide. It will explore the causes as well as the main solution to the problem.