Review of DRD4 GENE

$15.00

Order Now

Description

Review of DRD4 GENE

Review of DRD4 GENE

answer


DRD4 Gene is one of the most important genes in human body. It is a G-protein coupled receptor which is usually activated by a dopamine receptor in the cell. This gene is one of the targets by the drugs take to treat Schizophrenia and others like Parkinson disease.  In its action, the gene is shown to work like D2 in activating receptor which inhibits the action of Adenly cycles and therefore its action reduces intracellular concentration of Cyclic AMP which is the second messenger. The pharmacological and the genetic experiments carried out shows that the gene plays an important role in neurobehavioral processes like attention, motivational and exploratory. (Schmidt, et al., 2001)