Pathophysiological Processes of the Mother

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Pathophysiological Processes of the Mother

Pathophysiological Processes of the Mother

Hyperglycemia during pregnancy remains one of the challenges in the management of diabetes during pregnancy.    One of the main results of such complication is macrosomia.  Macrosomia results from maternal hyperglycemia during the second and third trimester in pregnancy.

Pathophysiological Processes of the Mother

Management of diabetes is therefore essential throughout the pregnancy to ensure that both the mother and the child are safe. However diabetic pregnancy is not the only factor which can lead to macrosomia. There are other identified genetic and other factors which are also causative factors for macrosomia.

Pathophysiological Processes of the Mother

However even with good glycemic control, macrosomia also occurs in a significant number of fetus of mothers with diabetes.  Macrosomia may lead to a number of complications including trauma during delivery and increased chances of undergoing cesarean delivery