Following the currently increasing global crimes, the world peace and security has been threatened. This has necessitated most countries across the world to engager in production or importation of weapons, in which of them have been found to have mass destruction. In this regard, the development of weapons of mss destruction in Mexico has been in alignment with the worlds changing trends of self protection in case of wars and other calamities. There have been various factors triggering the increase of weapons of mass destruction in Mexico, over the last few decades. Such actors are both intrinsic and extrinsic, as a result of the currently experienced world interactions among various countries (Davis 2006). This paper presents the factors which have triggered the increment of the Mexico’s weapons of mass destruction.