End-stage organ failure is one of the contemporary health challenges facing the world. With no cure, novel treatment options have been tried, the best being transplantation. Transplantation is preferred because of associated benefits like improved quality of life and possibleof long-term survival. Corneal transplantation is a preferred method of choice for treatment of corneal blindness, a condition that leads to total vision loss. Corneal blindness, which results from corneal damage, ranks second after cataract in the cause of blindness. The importance of corneal transplantation is further underpinned by statistics from the World Health Organization (WHO), which show that about 39 million people suffer from blindness, while another 285 million suffer from low vision. Statistics further shows that out of the reported 45 million cases of total blindness, corneal blindness comprises 6-8 million. Corneal blindness is caused by different factors including trachoma, ulceration of the corneal as a result of vitamin-A deficiency, using traditional eye medicine, neonatorumophthalmia, and many others.