Chronic Renal Failure and MCADD
Pain is not associated with chronic renal failure unless there is obstruction of urine especially arising from renal stones (NCBI, 2010). Pain is also be caused by infection of renal cysts or renal capsules especially in polycystic renal disease. If the urethra or the bladder is affected by inflammation resulting from infection, this causes discomfort to the patient (Smith & Hall, 2009).
During the earliest stages of chronic renal failure, symptoms may not be evident and as a result, patients may spend a long period of time without realizing that they have renal failure. Symptoms become noticeable when the rate of glomerular filtration is 20ml/minute with the capability of affecting other systems in the body (Edren, 2010). The most common symptom of chronic renal failure is general weakness and tiredness.