In the recent past, there has been great advancement in science and technology. Science is changing not only the way we do things but also the way we live. Advance in science and technology has been rooted for correction of a number of anomalies that the world is facing today, especially in regard to disease and reproduction. One of the interest areas in science has been genetic engineering. Advanced understanding of working of DNA materials has provided the base for correction of most disease conditions that have for long been stumbling block to a healthy life. However, the continued advancement in DNA technology, and its application in science and medical field, has come with many ethical challenges. There is a struggle between ensuring sustained use of DNA technology in medical and science field and dealing with the ethical issues that are arising as a result. For example, pre-implantation genetic diagnoses (PGD) has for long being used for medical purpose but progress of DNA technology behind PGD now pose a great threat to its continued use. Recent efforts have been geared towards using the technology not only for elimination of medical conditions that could alter individuals in later life but also for selection of sex and traits of the unborn child. In essence, this implies that the technology could soon be used to produce designer babies, if parents are given the right to select the traits of their children through this technique. This poses a great challenge because those who can afford will have advantage of selecting the sex and traits of their children, which means there will be more discrimination in the society. Although PGD and other DNA based technology have important medical use, their application outside the medical field poses a great ethical challenge.